Advancing Science, Changing Lives
Our breakthroughs are driven by a singular purpose: to improve the lives of those affected by rare diseases.
The Unmet Need
Patients with muscle-wasting diseases like Duchenne Muscular Dystrophy, sarcopenia, cachexia, and others face significant challenges, with a profound impact on their lives and families. Current treatment options remain inadequate, with a notable absence of therapies that meaningfully improve muscle function or address the underlying causes of disease.
Our Unique Approach
Sarcomatrix offers an innovative approach to muscular dystrophies, distinct from many other pharmaceutical companies. While competitors often focus on gene therapies or dystrophins, we target core muscle biology by influencing α7β1 integrin expression.
Complementary Potential
A key differentiator of Sarcomatrix’s compounds is their ability to complement other treatments in support of skeletal muscle, Early indicators suggest our therapy may support cardiac muscle health, addressing one of the leading causes of mortality. While current treatments, including gene therapies, primarily slow disease progression, our approach has the potential to reverse muscle loss and restore function. We envision a combined approach to maximize patient outcomes.
Preclinical Evidence
Promising results have been demonstrated in preclinical studies, showing stabilization and reversal of muscle damage in both small and large animal models. These studies have revealed strong systemic effects and notable improvements in cardiac function, supporting the potential for broad therapeutic impact.
The Breakthrough
Increasing alpha 7 integrin expression helps stabilize muscle tissue and potentially promotes regrowth and regeneration. This approach addresses the root causes of muscle degeneration and repair deficits.
Patient Impact
Our goal is to provide both immediate and long-term benefits, significantly improving patients’ quality of life. Our treatments have the potential to be effective regardless of the stage of diagnosis.
